4(3H)-Quinazolinone, 6-nitro- - Names and Identifiers
4(3H)-Quinazolinone, 6-nitro- - Physico-chemical Properties
Molecular Formula | C8H5N3O3
|
Molar Mass | 191.14 |
Density | 1?+-.0.1 g/cm3(Predicted) |
Melting Point | 286-287 °C |
Boling Point | 407.0±47.0 °C(Predicted) |
Flash Point | 199.9°C |
Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
Vapor Presure | 7.81E-07mmHg at 25°C |
Appearance | Solid |
Color | Yellow |
pKa | -1.01±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.739 |
4(3H)-Quinazolinone, 6-nitro- - Risk and Safety
4(3H)-Quinazolinone, 6-nitro- - Introduction
6-Nitroquinazolin-4 (1H)-one, chemical formula C8H4N4O3, is an organic compound. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-6-Nitroquinazolin-4 (1H)-one is a yellow to orange solid.
-It has a high melting point and thermal stability.
-Almost insoluble in water at room temperature, but soluble in some organic solvents such as chloroform, dichloromethane and dimethyl sulfoxide.
Use:
-6-Nitroquinazolin-4 (1H)-one is widely used in the field of organic synthesis.
-It can be used as a pharmaceutical intermediate for the synthesis of various biologically active compounds.
-In addition, it can also be used for the preparation of dyes, pigments and photosensitive materials.
Preparation Method:
- 6-nitroquinazolin-4(1H)-one can be synthesized by a variety of synthetic methods.
-One of the commonly used methods is to treat 3-nitro2-aminophenol with ketone, and then carry out acid-base neutralization to obtain the target compound.
Safety Information:
- 6-nitroquinazolin-4(1H)-one is an organic compound with certain potential hazards.
-It may irritate the eyes, skin and respiratory system, so avoid contact when handling.
-In operation, it is recommended to take appropriate laboratory safety measures, such as wearing protective gloves, goggles and protective clothing.
-During storage, it should be kept in a dry, cool place, away from fire and combustibles.
Last Update:2024-04-09 20:52:54